Description for medicine or protocol of treatment in detail:
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Acupuncture for regulating menstruation and promoting pregnancy
Needles: Needles and electroacupuncture instruments are from Suzhou Medical Supplies Factory Co., Ltd. (Registration number: Su Food and Drug Administration Approval No. 2001-0020; Registration Certificate No.: Su Xie Zhuzhun 20162270970). Needle model: Huatuo brand disposable acupuncture needle, length 75mm, thickness 0.30mm; length 40mm, thickness 0.25mm; length 25mm, thickness 0.25mm. Electroacupuncture instrument model: Huatuo brand electronic acupuncture instrument SDZ-II.
Acupoint selection: acupoint group 1: Baihui, Shenting, Zhongwan, Guanyuan and (bilateral) Benshen, Tianshu, Dahe, ovary (3 inches below the umbilicus, 3 inches beside the front midline), Zusanli, Sanyinjiao, Taixi, and Taichong points; point group 2: (bilateral) Shenshu and Ciliao points. For details, please refer to the 2006 Chinese National Standard (GB/T-11246-2006) "Acupoint Names and Positions".
Operation: The two-point groups are used alternately, and acupuncture is performed with sterile disposable acupuncture needles after routine disinfection. Use 0.25x25mm acupuncture needles at Baihui, Benshen, and Shenting to puncture 10-15mm backwards at an angle of 15 degrees. Twist only without lifting. The twisting frequency is 150 times/min for 1 min; Zhongwan and Tianshu Use 0.25 x 40mm acupuncture needles to directly puncture 20-30mm with 0.25 x 40mm acupuncture needles at Guanyuan, Dahe, Ovarian, Zusanli and Shenshu points; puncture 10-15mm with 0.25 x 25mm acupuncture needles at Sanyinjiao, Taixi and Taichong points; A 0.30 x 75mm acupuncture needle was used to puncture 40-50mm obliquely towards the midline at an angle of about 45 degrees, into the second posterior foramen, so that the needle sensation was transmitted to the perineum. All acupoints are required to get qi, and the needle should be kept for 30 minutes. Electroacupuncture: Connect the electrodes of the electroacupuncture instrument across the needle handles of both Shenshu and Zhongliu. Electroacupuncture parameters: density wave; 2/15Hz, the current intensity should be tolerable by the patient without discomfort, and the needle should be retained for 30 minutes.
Course of treatment: alternating acupuncture in the acupoint group 1 and the acupoint group 2, leaving the needle for 30 minutes each time, and treatment is performed 3 times a week for 12 weeks.
Fire dragon moxibustion
Materials: Moxa sticks are Qingmoxa sticks produced by Jiangsu Kangmei Pharmaceutical Co., Ltd. (manufacturing batch number: Z32020253); patients prepare crushed ginger powder.
Acupoint selection: the governor channel on the back and the bladder meridian area on both sides, and the abdomen Ren channel and Chongmai area. For details, please refer to the 2006 Chinese National Standard (GB/T-11246-2006) "Acupoint Names and Positions".
Operation: The patient first takes the prone position, takes the governor meridian on the back and the bladder meridian area on both sides, smears ginger juice, and then spreads a layer of rice paper with ground ginger with a thickness of 2-3cm, and finally spreads moxa on the ginger, thickness For 2-3cm, light moxa and apply moxibustion for 1 hour. After the moxibustion is over, the patient takes the supine position and moxibuses the region of the abdomen and Chongmai as described above for 1 hour.
Course of treatment: each treatment time is about 2 hours, once a week, continuous treatment for 12 weeks.
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Inclusion criteria
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1. Meet the diagnostic criteria:
(1)Aged <=18 years and <40 years;
(2)Clinical manifestations: abnormal menstruation, including oligomenorrhea or decreased menstrual flow, severe cases may cause amenorrhea and infertility; at the same time, it may be accompanied by perimenopausal symptoms, such as Soreness of waist and knees, dizziness, tinnitus, insomnia, facial flushing, hot sweating, irritability, fatigue, loss of libido, etc.
(3)10U/L < FSH < 25U/L;
(4)AMH < 1.1ng/mL;
(5)Antral follicle count < 7. It can be diagnosed with any one of (1), (2) and (3)-(5).
2. Sign informed consent and voluntarily participate in this research.
Note: Patients who meet the above 2 items at the same time can be included in this study.
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