Inclusion criteria
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Diagnostic criteria for dry eye: Eyes have symptoms such as dryness, foreign body sensation, burning sensation, fatigue, discomfort, vision fluctuations, tear film breakup time (BUT) ≤ 5 seconds, tear secretion test Ⅰ (Schirmer Ⅰ test) ) ≤5mm/5min, or BUT between 5-10 seconds, Schirmer Ⅰ test 5-10mm/5min and positive staining of corneal and conjunctival fluorescein.
Inclusion criteria: age between 20 and 70 years old; able to cooperate with diagnosis and treatment; sign informed consent and participate voluntarily; follow-up for 6 months.
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Exclusion criteria:
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Congenital lacrimation, conjunctivitis, keratitis, uveitis, scleritis, meibomian gland cysts and other eye diseases under treatment; ocular trauma caused by incomplete eyelid structure, eyelid scars, partial eyelid Deformities, etc.; organic diseases such as space-occupying eyes; trauma, hemorrhage, skin infections or skin diseases in the eyes; acute attacks of glaucoma, bleeding in the fundus, etc.; allergies to any component such as drugs; fever, severe heart disease Cerebrovascular diseases, infectious diseases, pregnant women, etc.; patients with diabetes, arthritis, connective tissue disease history, mental illness, cognitive impairment, etc.; patients currently taking antidepressants or anti-anxiety drugs
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