Description for medicine or protocol of treatment in detail:
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(1) Drug line group
Acupuncture: Referring to the "Eleventh Five-Year Plan" national planning textbook for general higher education, Edited by Shi Xuemin, Acupuncture and Moxibustion (Beijing: China Traditional Chinese Medicine Press, 2007). Select five acupuncture points on the face (Sun, Shimonoseki, Zygomatic, Four White, Ashi).
Operation method: (1) Preparation of the drug line: a total of ten acupuncture points on the face, ten threads are needed, and each 1 thread needs to be infiltrated in 0.2 ml of the liquid medicine; 10 threads are soaked in the 2 ml of tranexamic acid injection one hour in advance; take a medical absorbable thread, put it into the front end of the needle, the length of the thread in the needle tube hole and outside the hole is basically the same, and the remaining liquid can be sucked into the needle tube; Sterile conditions are guaranteed during preparation. (2) Treatment steps: instruct the patient to take the supine position, wear an opaque eye mask, routinely disinfect the skin of the acupuncture point, and when the needle is pierced into the acupuncture point, the thread is pressed at the tip of the needle to form a fold in half, and the acupuncture point is quickly pierced with the needle tip; After ensuring that the thread outside the needlehole enters the skin and obtains a needle feeling, the drug is injected (about 0.2 ml per acupuncture point) while retreating, until the needle body is withdrawn, and the thread body remains at the acupuncture point, that is, a drug-infiltrated thread is completed at the same time.
(2) Drug group
Acupuncture: same line group.
Operation method: the above-mentioned tranexamic acid injection is selected, the dosage is the same as the drug line group, and the facial acupuncture point is injected.
(3) Buried wire group
Acupuncture: same line group.
Operation method: the above absorbable surgical sutures are selected, and the implanted acupuncture points, levels, and methods are the same as the drug thread group, only the thread is injected, not the drug is injected.
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Inclusion criteria
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(1) Age 18 to 60 years old, female;
(2) Those who have not received acupuncture point burial thread treatment before;
(3) Meet the diagnostic criteria for melasma;
(4) The clinical stage is a stable stage;
(5) Each patient understands the purpose and method of this study before the trial, and voluntarily participates in it, and signs the informed consent of the trial Book.
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Exclusion criteria:
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(1) Pregnant or lactating women;
(2) Patients who are allergic to the use of drugs in this study;
(3) Patients with inflammatory or infectious skin diseases at the treatment site;
(4) Patients with severe endocrine, gynecological, cardiovascular and cerebrovascular diseases, abnormal coagulation function, abnormal liver and kidney function and tumors;
(5) Those who have received laser treatment, oral or topical freckle removal drugs in the past 1 month;
(6) If the sunscreen cannot be achieved as required during the treatment.
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